Portfolio Companies

develops reactive glass products and nanosands for remediation or site-cleanups of volatile organic and related spills, plumes or gas discharge.

develops and manufactures the Thermafficient™ engine, which recovers thermal energy from a wide variety of sources and transforms this energy into useable power and heat.

provides proprietary processes for the removal of metal contaminants from water and industrial fluid waste streams through the use of recycled alumina catalysts - transforming waste alumina catalysts into a major contributor for improving our environment.

develops, manufactures, and sells the most affordable all-electric vehicle in America today.

is developing and commercializing systems for growing algae and harvesting commercially viable energy products from the biomass: primarily algal oil (also called lipids) and methane gas.

is developing direct carbon fuel cells (DCFC) – fuel cells that use carbon rather than hydrogen as fuel. DCFCs directly convert readily available carbon fuels, generate distributed power that will be cost competitive with the grid, and realize considerable environmental benefits relative to current combustion technologies.

creates high-performance, low cost catalytic heat exchange and reactor solutions.

is an advanced materials company offering nanocomposite coatings and focused arc coating systems to industry.

designs light-emitting diode (LED) lighting products that improve the convenience and energy efficiency of current lighting solutions.

has commercialized a process for manufacturing dies and molds by spraying atomized molten tool steel onto a cast ceramic negative mold.

develops, produces, and markets leading refractory technologies for global molten processing companies.

has a novel platform analytical technology used to characterize liquids in industry and medical testing.

, located in Akron, Ohio, is developing and commercializing an alternative source of rubber for the $10B natural rubber market.

is developing and commercializing a line of high-tech, energy-curable, nanoparticle dispersions and coatings.

is an innovative tool that measures vaginal cervical length objectively to help identify women at risk for preterm labor during pregnancy.

is a Cleveland-based drug development company focused on the commercialization of repurposed drug candidates.

is a fast-growing healthcare technology and services company in Northeast and Central Ohio.

provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures for better patient outcomes.

is a clinical stage company focused on developing and commercializing products that prevent infections associated with indwelling catheters.

is a northeast Ohio based medical device company focused on the development and commercialization of minimally invasive neurostimulation technologies for the diagnosis and treatment of neurodegenerative impairments.

based in Cleveland and built on technology developed by Dr. Michael A. Weiss at Case Western Reserve Medical School, Thermalin Diabetes Incorporated is developing clinically-superior, second generation, insulin analogs for the rapidly-growing $12 billion insulin market.

, a Cleveland, Ohio-based neurostimulation company, is focused on developing neurostimulation therapies for unmet needs to patients worldwide.

is dedicated to reducing the risk, cost, and time associated with drug development by focusing on developing repurposed drugs for unserved vascular disease markets.

is commercializing a breakthrough technology that will significantly improve the diagnosis and treatment of a number of critical heart conditions.

designs, manufactures and markets innovative endoscopic accessory devices in the field of gastrointestinal (GI) endoscopy.

is a Cleveland Clinic spin-off company developing novel regenerative therapies for cardiovascular disease.

has developed a novel diagnostic imaging system to help surgeons identify later-stage osteoarthritis patients who are best suited for cartilage repair procedures or joint replacement surgery.

is a developmental stage medical device company focused on the commercialization of novel technologies for the management of diabetes.

is a Cleveland-based cancer diagnostics company that has developed and is presently commercializing a proprietary platform technology to improve cancer detection, diagnosis, progression, and prognosis.

is developing revolutionary MRI coil devices utilizing proprietary nanotechnology, which will produce higher image quality and faster scan times resulting in a significant boost of the functional capabilities of any installed MRI system.

provided remote daytime and nighttime radiology interpretations, performed within rapid turnaround times, by highly specialized radiologists.

is a leading provider of integrated employee scheduling and communications technology to optimize labor utilization and control labor costs for employers with shift based workforces.

is building advanced software technology designed to dramatically improve the performance of enterprise applications, data warehouses, and cloud computing infrastructures.

is a developer of software "obfuscation" and size reduction products designed to help businesses secure their intellectual property assets.

develops solutions to improve online search and lead generation for complex products and services.

is dedicated to commercializing an inertial tracking system for underground mines.

is a Software-as-a-Service (SaaS) company developing digital music services that help independent artists manage their music careers online.

has been providing voice software products to help businesses increase the effectiveness of their communications while driving down costs since 2002.

maximizes the ROI of direct digital marketing – interactive marketing communications that can be addressed to a specific individual – through process automation, increased relevance and improved performance.

develops and sells a proprietary Wireless Emergency Notification System ("WENS").

has a unique web native solution creates and maintains direct and instantaneous connections between manufacturers and distributors and their freight carriers.

is a business intelligence software company that uses proprietary database search and analytical tools to help R&D intensive companies enhance their strategic planning processes.

manufactures innovative high temperature pressure sensors that enable more precise control of diesel, gasoline and turbine engines in harsh environments.

manufactures silicon carbide-based pressure sensors designed to work in harsh (i.e. corrosive and/or very high temperature) environments.

is an early-stage e-commerce insurance company selling pet health insurance direct to pet owners, primarily via the internet.

is the nation’s leading producer and distributor of sports performance, training and lifestyle content for high school athletes and the high school sports community.

(formerly known as Charitee) is a leading provider of automated hole-in-one systems for golf courses.

, acquired by Yardi Systems in May 2010, is the developer of highly intuitive, web-based property management software solutions designed specifically for the independent rental owner and manager of apartment units or single-family dwellings.

(formerly Heritage Fare) develops, manufactures and markets innovative food technologies that enhance food flavor while minimizing fat content.

offers in-store merchandising services and programs for urban consumers and retailers.